Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.49 |
| ▸ | THRA | P10827 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829095 | 0.82 | MEN1 (0.58) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL7477395 | 0.80 | THRB (0.53) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL24781304 | 0.80 | THRB (0.55) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL7999085 | 0.79 | THRB (0.53) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL7473889 | 0.78 | THRB (0.53) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL7475466 | 0.76 | THRB (0.52) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL7472949 | 0.76 | MEN1 (0.51) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL8347711 | 0.76 | THRB (0.52) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL7481956 | 0.76 | THRB (0.52) | THRBTHRAMEN1NR1I2KMT2A | |
| SCHEMBL7989678 | 0.75 | NOTUM (0.38) | MEN1KMT2ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294536-B1 | CONTROL OF PROTOZOA AND REDUCTION IN THE INCIDENCE OF ASSOCIATED DISEASES AND DEATH AND CONSEQUENT IMPROVEMENT IN RETARDED GROWTH AND GENERAL CONDITION AND PREVENTING DECREASE GROWTH AND GENERAL CONDITION | TAKEDA SCHERING-PLOUGH ANIMAL HEALTH K.K. (JP) | 2001-09-25 | — | — | US | disclosed |