Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.54 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.54 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989208 | 0.92 | PIN1 (0.61) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL7991660 | 0.89 | MAPT (0.49) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL7977701 | 0.88 | MAPT (0.59) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL7995168 | 0.87 | MAPT (0.51) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL7988193 | 0.86 | MAPT (0.52) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL7978081 | 0.86 | MAPT (0.52) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL7988557 | 0.85 | PIN1 (0.58) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL2954980 | 0.84 | ALOX5 (0.60) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL7988400 | 0.83 | PIN1 (0.47) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL7989018 | 0.81 | MAPT (0.47) | MEN1KMT2AMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |