Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.51 |
| ▸ | RAF1 | P04049 | 1/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988569 | 0.92 | ALOX5 (0.48) | TARBP2ALOX5MAPTKDM4EKMT2A | |
| SCHEMBL7989451 | 0.91 | ALOX5 (0.58) | MAPK13MAPK12MAPK11MAPK14ALOX5 | |
| SCHEMBL7989597 | 0.90 | SIRT2 (0.53) | TARBP2ALOX5MAPTKDM4EKMT2A | |
| SCHEMBL7990062 | 0.90 | SIRT2 (0.53) | TARBP2ALOX5MAPTKDM4EKMT2A | |
| SCHEMBL28582964 | 0.89 | TARBP2 (0.54) | TARBP2ALOX5MAPTKDM4EKMT2A | |
| SCHEMBL28576642 | 0.87 | ERCC1 (0.55) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL7991922 | 0.86 | AR (0.50) | MAPK13MAPK12MAPK11MAPK14ALOX5 | |
| SCHEMBL6367621 | 0.86 | ERCC1 (0.54) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL7989869 | 0.85 | KDM4E (0.43) | MAPK13MAPK12MAPK11MAPK14DHODH | |
| SCHEMBL17803252 | 0.84 | KDM4E (0.58) | DHODHALOX5MAPTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |