Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.42 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989451 | 0.92 | ALOX5 (0.58) | ALOX5KDM4EMAPTMEN1HSP90AA1 | |
| SCHEMBL7989950 | 0.92 | MAPK13 (0.51) | ALOX5KDM4EMAPTMEN1HSP90AA1 | |
| SCHEMBL7990062 | 0.91 | SIRT2 (0.53) | ALOX5KDM4EMAPTMEN1HSP90AA1 | |
| SCHEMBL7989597 | 0.91 | SIRT2 (0.53) | ALOX5KDM4EMAPTMEN1HSP90AA1 | |
| SCHEMBL7991922 | 0.87 | AR (0.50) | ALOX5KDM4EMAPTMEN1HSP90AA1 | |
| SCHEMBL7991775 | 0.87 | ALOX5 (0.59) | ALOX5KDM4ETARBP2TP53SMN1; SMN2 | |
| SCHEMBL17803252 | 0.85 | KDM4E (0.58) | ALOX5KDM4EMAPTMEN1HSP90AA1 | |
| SCHEMBL7992000 | 0.84 | MAPT (0.50) | ALOX5KDM4EMAPTMEN1HSP90AA1 | |
| SCHEMBL7988191 | 0.84 | NPBWR1 (0.53) | KDM4EMEN1KMT2ANPBWR1PARP1 | |
| SCHEMBL7989869 | 0.82 | KDM4E (0.43) | ALOX5KDM4EMAPTMEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |