Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511715 | 0.93 | NPSR1 (0.41) | NPSR1TSHRGAAALDH1A1HPGD | |
| SCHEMBL7510667 | 0.89 | NPSR1 (0.39) | NPSR1TSHRGAAALDH1A1HPGD | |
| SCHEMBL7450924 | 0.89 | NPSR1 (0.39) | NPSR1TSHRGAAALDH1A1HPGD | |
| SCHEMBL7517976 | 0.88 | ALDH1A1 (0.45) | TSHRGAAALDH1A1HPGDMAPK1 | |
| SCHEMBL7990187 | 0.88 | ALDH1A1 (0.45) | TSHRGAAALDH1A1HPGDMAPK1 | |
| SCHEMBL7992780 | 0.83 | IDO1 (0.41) | NPSR1GAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL7989199 | 0.83 | SLC1A3 (0.45) | TSHRGAAALDH1A1MAPK1KDM4E | |
| SCHEMBL7989889 | 0.81 | CA1 (0.47) | TSHRGAAMAPK1HTTMEN1 | |
| SCHEMBL7989942 | 0.81 | CA1 (0.47) | TSHRGAAMAPK1HTTMEN1 | |
| SCHEMBL7509273 | 0.81 | CA1 (0.47) | TSHRGAAMAPK1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |