Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989982 | 0.93 | ACLY (0.35) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL7989990 | 0.86 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHR | |
| SCHEMBL3169686 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL27256409 | 0.75 | ACLY (0.37) | CYP3A4ACLY | |
| SCHEMBL386942 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL7990009 | 0.74 | ACLY (0.31) | ACLY | |
| SCHEMBL29446627 | 0.72 | CYP3A4 (0.55) | ALDH1A1TDP1LMNACYP3A4 | |
| SCHEMBL18342581 | 0.72 | ACLY (0.42) | LMNACYP3A4ACLY | |
| SCHEMBL18342582 | 0.72 | ACLY (0.42) | LMNACYP3A4ACLY | |
| SCHEMBL16327143 | 0.71 | ACLY (0.34) | ALDH1A1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117594-A1 | FLUORINATED MACROCYCLIC COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |