Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2414856 | 1.00 | ALDH1A1 (0.47) | ALDH1A1GDACYP3A4PMP22MAPK1 | |
| Hydrochloric Acid SCHEMBL29540090 | 0.98 | ALDH1A1 (0.45) | ALDH1A1GDACYP3A4PMP22MAPK1 | |
| SCHEMBL20187696 | 0.87 | ALDH1A1 (0.42) | ALDH1A1GDACYP3A4PMP22MAPK1 | |
| SCHEMBL20189112 | 0.83 | ALDH1A1 (0.45) | ALDH1A1GDABRD4RAB9APOLB | |
| SCHEMBL21353906 | 0.81 | GDA (0.42) | ALDH1A1GDACYP3A4PMP22MAPK1 | |
| SCHEMBL1866524 | 0.78 | ADORA2A (0.50) | ALDH1A1POLBBLMADORA2APDE4A | |
| SCHEMBL25100643 | 0.77 | ADORA2A (0.47) | ALDH1A1BRD4RAB9APOLBLMNA | |
| SCHEMBL7046793 | 0.75 | ALDH1A1 (0.41) | ALDH1A1BRD4RAB9APOLBLMNA | |
| Guanine SCHEMBL21840391 | 0.73 | PNP (0.68) | ALDH1A1GDACYP3A4PMP22MAPK1 | |
| SCHEMBL2115743 | 0.73 | ALDH1A1 (0.52) | ALDH1A1CYP3A4PMP22LMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |