SCHEMBL7990271

SCHEMBL7990271

Cc1ccc(Cc2ccccc2)c(C)c1C

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.46
BCL2 P10415 1/20 0.43
BCL2L1 Q07817 1/20 0.43
CTRC Q99895 3/20 0.43
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42
ALOX5 P09917 1/20 0.42
NPC1 O15118 1/20 0.42
HPGD P15428 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CNR2 P34972 2/20 0.42
GPR55 Q9Y2T6 2/20 0.42
HTR2A P28223 1/20 0.41
LDHA P00338 1/20 0.41
LDHB P07195 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8098213 0.91 CALM1 (0.55) CALM1BCL2BCL2L1CTRCALOX5
SCHEMBL1276090 0.84 CALM1 (0.48) CALM1BCL2BCL2L1CYP3A4CYP2D6
SCHEMBL2843915 0.83 CALM1 (0.42) CALM1BCL2BCL2L1CYP3A4CYP2D6
SCHEMBL8005691 0.83 TP53 (0.48) CALM1BCL2BCL2L1CTRCALOX5
Ammonia Solution, Strong SCHEMBL27502158 0.83 CALM1 (0.46) CALM1BCL2BCL2L1CYP3A4CYP2D6
SCHEMBL8932351 0.83 POLB (0.47) CALM1BCL2BCL2L1CTRCCYP3A4
SCHEMBL27806559 0.83 IDO1 (0.39) CYP3A4CYP2D6TSHRCYP2C19CNR2
SCHEMBL28784572 0.82 BCL2 (0.48) BCL2BCL2L1CYP3A4CYP2D6TSHR
SCHEMBL10354583 0.81 BCL2 (0.47) CALM1BCL2BCL2L1CYP3A4CYP2D6
SCHEMBL11208418 0.81 HTR2A (0.48) CALM1BCL2BCL2L1CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4006814-A None JP disclosed
JP-4006815-A None JP disclosed
CN-109661449-A Sealing material composition, liquid crystal cell, and method for producing liquid crystal cell 夏普株式会社 2019-04-19 CN disclosed
CN-106535815-A Reactive micro-applicator with metal-containing additives for applying dental adhesives 贺利氏古萨有限公司 2017-03-22 CN disclosed
US-6127314-A HAVING HIGHLY TRANSPARENT HEAT-SENSITIVE LAYER COMPRISING COLORLESS ELECTRON DONATIVE DYE PRECURSOR INSIDE MICROCAPSULES; AND SOLID PARTICLES OF RELATIVELY LARGE DIAMETER IN A DISPERSION; AND HIGH COLOR FORMING SENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 2000-10-03 US disclosed
JP-H046815-A OIL-IMPREGNATED CAPACITOR NISSIN ELECTRIC CO LTD 1992-01-10 JP disclosed
JP-H046814-A OIL-IMPREGNATED CAPACITOR NISSIN ELECTRIC CO LTD 1992-01-10 JP disclosed