Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 3/20 | 0.30 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838791 | 0.91 | ALDH1A1 (0.35) | ALDH1A1PKMDAOKDM4AKDM4C | |
| SCHEMBL8005167 | 0.90 | PRMT5 (0.31) | — | |
| SCHEMBL8001879 | 0.90 | — | — | |
| SCHEMBL7998640 | 0.89 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL8002371 | 0.88 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL8000276 | 0.87 | GSK3A (0.30) | — | |
| SCHEMBL8002347 | 0.86 | PRMT5 (0.30) | — | |
| SCHEMBL7999093 | 0.86 | — | — | |
| SCHEMBL8005151 | 0.86 | — | — | |
| SCHEMBL7998698 | 0.86 | CYP17A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294536-B1 | CONTROL OF PROTOZOA AND REDUCTION IN THE INCIDENCE OF ASSOCIATED DISEASES AND DEATH AND CONSEQUENT IMPROVEMENT IN RETARDED GROWTH AND GENERAL CONDITION AND PREVENTING DECREASE GROWTH AND GENERAL CONDITION | TAKEDA SCHERING-PLOUGH ANIMAL HEALTH K.K. (JP) | 2001-09-25 | — | — | US | disclosed |