SCHEMBL8000276

SCHEMBL8000276

Cc1ccc(C(O)c2ccc(Cc3c(Cl)cc(N4N=CCNC4=O)cc3Cl)cc2)cn1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.30
GSK3B P49841 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7998640 0.91 ALDH1A1 (0.30)
SCHEMBL7999021 0.88
SCHEMBL8001879 0.88
SCHEMBL8002371 0.88 SMN1; SMN2 (0.38)
SCHEMBL7990341 0.87 ALDH1A1 (0.33)
SCHEMBL8005273 0.86 P2RX7 (0.33)
SCHEMBL7998970 0.85
SCHEMBL8005550 0.85
SCHEMBL7829919 0.84 THRA (0.31)
SCHEMBL8002369 0.84 FAAH (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6294536-B1 CONTROL OF PROTOZOA AND REDUCTION IN THE INCIDENCE OF ASSOCIATED DISEASES AND DEATH AND CONSEQUENT IMPROVEMENT IN RETARDED GROWTH AND GENERAL CONDITION AND PREVENTING DECREASE GROWTH AND GENERAL CONDITION TAKEDA SCHERING-PLOUGH ANIMAL HEALTH K.K. (JP) 2001-09-25 US disclosed