SCHEMBL29723905

SCHEMBL29723905

Cc1cccc(NC(=O)c2ccccn2)c1.Cc1cccc(NC(=O)c2ccccn2)c1

nearest known ligand 0.72

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDR P35968 6/20 0.72
GRM4 Q14833 7/20 0.70
HDAC6 Q9UBN7 1/20 0.70
KCNK3 O14649 1/20 0.68
KCNK9 Q9NPC2 1/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
NPC1 O15118 1/20 0.68
RAB9A P51151 1/20 0.68
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
ALDH1A1 P00352 1/20 0.65
LMNA P02545 1/20 0.65
CES1 P23141 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30643208 1.00 KDR (0.72) KDRGRM4HDAC6KCNK3KCNK9
SCHEMBL259238 1.00 KDR (0.72) KDRGRM4HDAC6KCNK3KCNK9
SCHEMBL7990375 0.89 KDR (0.84) KDRGRM4HDAC6KCNK3KCNK9
SCHEMBL28036432 0.87 GAA (0.66) KDRGRM4HDAC6KCNK3KCNK9
SCHEMBL28871825 0.87 GAA (0.58) KDRGRM4HDAC6KCNK3KCNK9
SCHEMBL259290 0.84 RAB9A (0.69) SMN1; SMN2NPC1RAB9AMEN1KMT2A
SCHEMBL12197847 0.84 GRM4 (0.76) KDRGRM4SMN1; SMN2NPC1RAB9A
SCHEMBL29496401 0.83 GRM4 (1.00) KDRGRM4HDAC6KCNK3KCNK9
SCHEMBL2528081 0.83 GRM4 (0.72) KDRGRM4HDAC6KCNK3KCNK9
SCHEMBL2530324 0.83 GRM4 (1.00) KDRGRM4HDAC6KCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119803926-A Rolling bearing fault diagnosis method, device, equipment, medium and product 武汉优泰电子技术有限公司 2025-04-11 CN claimed
EP-4406957-B1 ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME NOGRA PHARMA LTD (IE) 2026-04-08 EP disclosed
US-12577256-B2 Aryl receptor modulators and methods of making and using the same NOGRA PHARMA LIMITED (IE) 2026-03-17 US disclosed
WO-2025215004-A1 MANUAL PUMP ALPLA WERKE ALWIN LEHNER GMBH & CO KG (AT) 2025-10-16 WO disclosed
EP-4630973-A1 METHOD FOR OBTAINING A DATA GRID CONTAINING DATA REPRESENTATIVE OF A DYNAMICALLY REPRESENTED SCENE, AND CORRESPONDING DEVICE AND PROGRAM Institut National de Recherche en Informatique et en Automatique (FR) 2025-10-15 EP disclosed
CN-119803926-A Rolling bearing fault diagnosis method, device, equipment, medium and product 武汉优泰电子技术有限公司 2025-04-11 CN disclosed
US-20250066384-A1 ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME NOGRA PHARMA LIMITED (IE) 2025-02-27 US disclosed
EP-4437485-A2 TRANSACTION PLATFORMS WHERE SYSTEMS INCLUDE SETS OF OTHER SYSTEMS Strong Force TX Portfolio 2018, LLC (US) 2024-10-02 EP disclosed
EP-4406957-A2 ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME Nogra Pharma Limited (IE) 2024-07-31 EP disclosed
US-12042507-B2 Compositions and methods of modulating HIF-2A to improve muscle generation and repair UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2024-07-23 US disclosed
EP-3160964-B1 ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME NOGRA PHARMA LTD (IE) 2024-03-13 EP disclosed
CN-116947880-A Aryl receptor modulators and methods of making and using the same 诺格拉制药有限公司 2023-10-27 CN disclosed
EP-4262831-A1 METHODS OF CELL THERAPIES Ossium Health, Inc. (US) 2023-10-25 EP disclosed
CN-111978319-B Aryl receptor modulators and methods of making and using the same 诺格拉制药有限公司 2023-08-11 CN disclosed
US-20230234963-A1 ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME NOGRA PHARMA LIMITED (IE) 2023-07-27 US disclosed
WO-2023097026-A2 TRANSACTION PLATFORMS WHERE SYSTEMS INCLUDE SETS OF OTHER SYSTEMS Strong Force TX Portfolio 2018, LLC (US) 2023-06-01 WO disclosed
CN-116009741-A Clock dial for electronic device 苹果公司 2023-04-25 CN disclosed
US-11427600-B2 Aryl receptor modulators and methods of making and using the same NOGRA PHARMA LIMITED (IE) 2022-08-30 US disclosed
EP-4031685-A2 IN VITRO FERTILISATION (IVF) EMBRYO VIABILILITY AND QUALITY ASSAY University of Tartu (EE) 2022-07-27 EP disclosed
WO-2022133282-A1 METHODS OF CELL THERAPIES Ossium Health, Inc. (US) 2022-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577256-B2 Aryl receptor modulators and methods of making and using the same AHR, IL23R, ARNT KDR 1208/4885GRM4 2239/4885HDAC6 2095/4885
US-20250066384-A1 ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME AHR, IFNAR1, IL23R KDR 1063/4885GRM4 1487/4885HDAC6 1025/4885
US-11427600-B2 Aryl receptor modulators and methods of making and using the same AHR, IL23R, IL2RA KDR 1016/4885GRM4 1206/4885HDAC6 1163/4885
US-12042507-B2 Compositions and methods of modulating HIF-2A to improve muscle generation and repair HIF1A, HIF1AN, MYLK2 KDR 659/4885GRM4 4028/4885HDAC6 1165/4885
US-20230234963-A1 ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME AHR, IL23R, IL2RA KDR 1016/4885GRM4 1206/4885HDAC6 1163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.