Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.56 |
| ▸ | FLT1 | P17948 | 1/20 | 0.56 |
| ▸ | FLT4 | P35916 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.35 |
| ▸ | BRD7 | Q9NPI1 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545417 | 0.93 | KDR (0.52) | KDRFLT1FLT4CNR2HTR6 | |
| SCHEMBL7504851 | 0.92 | KDR (0.51) | KDRFLT1FLT4CNR2HTR6 | |
| SCHEMBL7547229 | 0.92 | KDR (0.51) | KDRFLT1FLT4CNR2HTR6 | |
| SCHEMBL7546769 | 0.91 | KDR (0.51) | KDRFLT1FLT4CNR2HTR6 | |
| SCHEMBL7990474 | 0.88 | KDR (0.71) | KDRFLT1FLT4CNR2 | |
| SCHEMBL7549333 | 0.86 | KDR (0.43) | KDRFLT1FLT4CNR2HTR6 | |
| SCHEMBL7550357 | 0.83 | KDR (0.78) | KDRFLT1FLT4PRKACAPRKACG | |
| SCHEMBL7549622 | 0.82 | KDR (0.55) | KDRFLT1FLT4CNR2HTR6 | |
| SCHEMBL7977281 | 0.81 | KDR (0.61) | KDRFLT1FLT4HTR6PRKACA | |
| SCHEMBL7547790 | 0.80 | KDR (0.68) | KDRFLT1FLT4BRD4PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265403-B1 | TYROSINE INHIBITORS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |