Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL3807945 | 0.91 | THRB (0.42) | TSHRALDH1A1CA1CA2THRB | |
| SCHEMBL124126 | 0.87 | ADRB2 (0.53) | TSHRADRB2ADRB1ADRB3CYP3A4 | |
| Ether SCHEMBL2530474 | 0.84 | TSHR (0.60) | TSHRADRB2ADRB1ADRB3CYP3A4 | |
| SCHEMBL3220182 | 0.84 | — | — | |
| Ether SCHEMBL11182899 | 0.84 | TSHR (0.60) | TSHRADRB2ADRB1ADRB3CYP3A4 | |
| Ether SCHEMBL8463434 | 0.84 | TSHR (0.52) | TSHRADRB2ADRB1ADRB3CYP3A4 | |
| SCHEMBL19177617 | 0.83 | ADRB2 (0.50) | TSHRADRB2ADRB1ADRB3CYP3A4 | |
| Hexane SCHEMBL15397882 | 0.83 | TSHR (0.50) | TSHRADRB2ADRB1ADRB3CYP3A4 | |
| SCHEMBL789967 | 0.83 | ADRB2 (0.50) | TSHRADRB2ADRB1ADRB3CYP3A4 | |
| SCHEMBL28650711 | 0.83 | ADRB2 (0.50) | TSHRADRB2ADRB1ADRB3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1011609-A4 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MEDLOGIC GLOBAL CORP (US) | 2000-08-16 | — | — | EP | disclosed |
| EP-1011609-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MedLogic Global Corporation (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1998050005-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MEDLOGIC GLOBAL CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |