Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Triphenylphosphine Oxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triphenylphosphine Oxide SCHEMBL27952745 | 1.00 | CA2 (0.55) | CA2CA4CA5ALMNACFTR | |
| Triphenylphosphine Oxide SCHEMBL3949 | 0.97 | CA2 (0.58) | CA2CA4CA5ALMNACFTR | |
| Triphenylphosphine Oxide SCHEMBL513223 | 0.97 | CA2 (0.58) | CA2CA4CA5ALMNACFTR | |
| Triphenylphosphine Oxide SCHEMBL3753871 | 0.93 | CA2 (0.55) | CA2CA4CA5ALMNACFTR | |
| Triphenylphosphine Oxide SCHEMBL8431251 | 0.93 | CA2 (0.63) | CA2CA4CA5ALMNACFTR | |
| Triphenylphosphine Oxide SCHEMBL11214761 | 0.93 | CA2 (0.55) | CA2CA4CA5ALMNACFTR | |
| Triphenylphosphine Oxide SCHEMBL7551485 | 0.93 | CA2 (0.55) | CA2CA4CA5ALMNACFTR | |
| SCHEMBL132983 | 0.93 | LMNA (0.60) | CA2CA4CA5ALMNACFTR | |
| SCHEMBL5439069 | 0.93 | LMNA (0.60) | CA2CA4CA5ALMNACFTR | |
| Triphenylphosphine Oxide SCHEMBL9425396 | 0.93 | CA2 (0.55) | CA2CA4CA5ALMNACFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118256226-A | Preparation method and application of red light perovskite quantum dot solution | 深圳大学 | 2024-06-28 | — | — | CN | disclosed |
| US-6103934-A | PROCESS CONTROL METHOD FOR THE PRODUCTION OF ACETIC ACID BY THE CATALYZED CARBONYLATION OF METHANOL | MILLENNIUM PETROCHEMICALS, INC. (US) | 2000-08-15 | — | — | US | disclosed |