Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | USP5 | P45974 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1984108 | 0.83 | HPGD (0.46) | ALDH1A1KMT2AMEN1CYP1A2LMNA | |
| SCHEMBL28946645 | 0.81 | CYP1A2 (0.46) | KMT2ACYP1A2LMNAPOLBGABRA1 | |
| SCHEMBL28946647 | 0.81 | CYP1A2 (0.46) | KMT2ACYP1A2LMNAPOLBGABRA1 | |
| SCHEMBL7026997 | 0.80 | GABRA1 (0.41) | ALDH1A1KMT2AMEN1CYP1A2LMNA | |
| Hydrogen Peroxide SCHEMBL29233362 | 0.80 | SOAT1 (0.49) | ALDH1A1KMT2AMEN1HTT | |
| Hydrogen Peroxide SCHEMBL27597692 | 0.80 | SOAT1 (0.49) | ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL11458981 | 0.80 | USP5 (0.58) | NR4A2USP5ALDH1A1GAAKMT2A | |
| SCHEMBL28946611 | 0.79 | GABRA1 (0.42) | ALDH1A1KMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL28946612 | 0.79 | GABRA1 (0.42) | ALDH1A1KMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL28216154 | 0.79 | HTT (0.49) | ALDH1A1KMT2AMEN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071475-A1 | UREA DERIVATIVES HAVING PI3K-INHIBITING ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071475-A1 | UREA DERIVATIVES HAVING PI3K-INHIBITING ACTIVITY | MTOR, STAT3, SLC14A1 | NR4A2 1831/4885USP5 244/4885ALDH1A1 3750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.