Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | BACE1 | P56817 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HTR3A | P46098 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyramine SCHEMBL7991337 | 0.92 | ALDH1A1 (0.64) | TAAR1ALDH1A1BACE1KDM4EHTR1A | |
| Tyramine SCHEMBL7999818 | 0.88 | ALDH1A1 (0.58) | TAAR1ALDH1A1BACE1CYP1A2KDM4E | |
| Tyramine SCHEMBL8002976 | 0.87 | TAAR1 (0.72) | TAAR1ALDH1A1BACE1CYP1A2CYP2A6 | |
| Tyramine SCHEMBL8001418 | 0.82 | TAAR1 (0.64) | TAAR1ALDH1A1BACE1KDM4EHTR1A | |
| Tyramine SCHEMBL8003448 | 0.81 | CYP2C19 (0.50) | TAAR1ALDH1A1BACE1CYP1A2KDM4E | |
| Tyramine SCHEMBL7999972 | 0.81 | ALDH1A1 (0.50) | TAAR1ALDH1A1BACE1CYP1A2KDM4E | |
| Tyramine SCHEMBL8006818 | 0.81 | TAAR1 (0.62) | TAAR1ALDH1A1BACE1CYP2A6KDM4E | |
| Tyramine SCHEMBL8003416 | 0.80 | KMT2A (0.50) | TAAR1ALDH1A1BACE1KDM4EHTR1A | |
| SCHEMBL8356905 | 0.80 | TAAR1 (0.86) | TAAR1ALDH1A1BACE1CYP1A2CYP2A6 | |
| Tyramine SCHEMBL8003673 | 0.79 | TAAR1 (0.55) | TAAR1ALDH1A1BACE1CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |