Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | HTR3A | P46098 | 1/20 | 0.64 |
| ▸ | BACE1 | P56817 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyramine SCHEMBL7999818 | 0.95 | ALDH1A1 (0.58) | ALDH1A1TAAR1KDM4EHTR1AADRA2A | |
| Tyramine SCHEMBL8002976 | 0.94 | TAAR1 (0.72) | ALDH1A1TAAR1KDM4EHTR1AADRA2A | |
| Tyramine SCHEMBL7991036 | 0.92 | TAAR1 (0.55) | ALDH1A1TAAR1KDM4EHTR1AADRA2A | |
| Tyramine SCHEMBL8001418 | 0.89 | TAAR1 (0.64) | ALDH1A1TAAR1KDM4EHTR1AADRA2A | |
| Tyramine SCHEMBL7999972 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TAAR1KDM4EHTR1AADRA2A | |
| Tyramine SCHEMBL8003448 | 0.88 | CYP2C19 (0.50) | ALDH1A1TAAR1KDM4EHTR1AADRA2A | |
| Tyramine SCHEMBL8006818 | 0.88 | TAAR1 (0.62) | ALDH1A1TAAR1KDM4EHTR1AADRA2A | |
| 4-Aminophenol SCHEMBL8001475 | 0.84 | ALDH1A1 (0.65) | ALDH1A1KDM4EBLMKMT2AALOX15 | |
| Tyramine SCHEMBL8003416 | 0.84 | KMT2A (0.50) | ALDH1A1TAAR1KDM4EHTR1AADRA2A | |
| Tyramine SCHEMBL8003312 | 0.83 | TAAR1 (0.56) | ALDH1A1TAAR1KDM4EHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |