Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11800875 | 0.87 | IDO1 (0.65) | MAPTCYP3A4LMNATP53ADORA3 | |
| SCHEMBL28261883 | 0.85 | MAPT (0.58) | MAPTCYP3A4LMNATP53ADORA3 | |
| SCHEMBL17744895 | 0.84 | SMN1; SMN2 (0.54) | MAPTCYP3A4LMNATP53ADORA3 | |
| SCHEMBL27810842 | 0.83 | KMT2A (0.54) | MAPTCYP3A4LMNATP53ADORA3 | |
| SCHEMBL8003577 | 0.81 | IDO1 (0.49) | MAPTCYP3A4LMNATP53ADORA3 | |
| SCHEMBL28261885 | 0.79 | MAPT (0.60) | MAPTCYP3A4LMNATP53ADORA3 | |
| SCHEMBL27779881 | 0.79 | MAPT (0.79) | MAPTCYP3A4LMNATP53ADORA3 | |
| SCHEMBL28150196 | 0.79 | MAPT (0.56) | MAPTCYP3A4LMNATP53ADORA3 | |
| SCHEMBL28261900 | 0.79 | MAPT (0.49) | MAPTCYP3A4LMNATP53ADORA3 | |
| SCHEMBL8006520 | 0.78 | IDO1 (0.66) | MAPTCYP3A4LMNATP53ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |