Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | F12 | P00748 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581562 | 0.84 | KMT2A (0.67) | MAPTKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL23199763 | 0.81 | ALDH1A1 (0.51) | MAPTKMT2AMEN1TDP1F12 | |
| SCHEMBL7991044 | 0.81 | MAPT (0.55) | IDO1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL7996110 | 0.80 | IDO1 (0.49) | IDO1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL11800875 | 0.80 | IDO1 (0.65) | IDO1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL29257065 | 0.79 | CYP3A4 (0.49) | MAPTKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL8001666 | 0.78 | IDO1 (0.50) | IDO1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL3502987 | 0.77 | KMT2A (0.60) | MAPTKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL8006532 | 0.77 | IDO1 (0.56) | IDO1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL8003434 | 0.75 | IDO1 (0.50) | IDO1MAPTKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |