Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 5/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454024 | 0.84 | KCNA3 (0.57) | KCNA3NR3C1HTTKDM4ELMNA | |
| SCHEMBL6604458 | 0.80 | KDM4E (0.56) | KCNA3KDM4ECYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL94801 | 0.79 | KCNA3 (0.61) | KCNA3NR3C1HTTKDM4ELMNA | |
| SCHEMBL14251166 | 0.79 | KCNA3 (0.61) | KCNA3NR3C1HTTKDM4ELMNA | |
| SCHEMBL11144866 | 0.79 | KCNA3 (0.61) | KCNA3NR3C1HTTKDM4ELMNA | |
| Water SCHEMBL9707280 | 0.78 | KDM4E (0.54) | KCNA3KDM4ECYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL6283416 | 0.78 | KCNA3 (0.57) | KCNA3NR3C1HTTKDM4ELMNA | |
| SCHEMBL7344375 | 0.77 | KDM4E (0.67) | KCNA3NR3C1KDM4ELMNACYP1A2 | |
| SCHEMBL4763782 | 0.76 | KCNA3 (0.55) | KCNA3NR3C1HTTKDM4ELMNA | |
| SCHEMBL5449325 | 0.76 | KCNA3 (0.67) | KCNA3NR3C1KDM4ELMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291432-B1 | (R)-N-(2-METHYLBENZYL)-3-((2S, 3S)-3-(N-(2-CHROMONECARBONYL)-L-ASPARAGINYL)AMINO-2-HYDROXY-4-PHENYLBUTANO YL)-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXAMIDE CAN BE GIVEN AS A TYPICAL EXAMPLE OF THIS COMPOUND. | JAPAN ENERGY CORPORATION (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-0900566-A1 | NOVEL TRIPEPTIDE COMPOUNDS AND ANTI-AIDS DRUGS | JAPAN ENERGY CORPORATION (JP) | 1999-03-10 | — | — | EP | disclosed |