SCHEMBL7991263

SCHEMBL7991263

CCCOCCCc1c[nH]cn1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.33
GBA1 P04062 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7988948 0.90 MEN1 (0.38) HRH3
SCHEMBL7991392 0.88 HRH3 (0.33) HRH3
SCHEMBL4385056 0.85 HRH3 (0.32) HRH3
SCHEMBL7977343 0.85 HRH3 (0.32) HRH3
SCHEMBL4386652 0.84 HRH3 (0.31) HRH3
SCHEMBL4376138 0.82 HRH3 (0.32) HRH3
SCHEMBL4385141 0.82 HRH3 (0.34) HRH3
SCHEMBL4383571 0.82 HRH3 (0.52) HRH3
SCHEMBL793540 0.81
SCHEMBL4379813 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996029315-A2 IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 1996-09-26 WO claimed
US-6248765-B1 ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) 2001-06-19 US disclosed