Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977259 | 0.90 | TLR7 (0.36) | HRH3TLR7 | |
| SCHEMBL7991263 | 0.85 | HRH3 (0.33) | HRH3 | |
| SCHEMBL4385056 | 0.84 | HRH3 (0.32) | HRH3 | |
| SCHEMBL7991392 | 0.83 | HRH3 (0.33) | HRH3SMN1; SMN2 | |
| SCHEMBL4386652 | 0.82 | HRH3 (0.31) | HRH3 | |
| SCHEMBL2286231 | 0.82 | — | — | |
| SCHEMBL7988948 | 0.82 | MEN1 (0.38) | HRH3SMN1; SMN2 | |
| SCHEMBL9999610 | 0.81 | — | — | |
| SCHEMBL4385141 | 0.81 | HRH3 (0.34) | HRH3 | |
| SCHEMBL4376138 | 0.81 | HRH3 (0.32) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |