Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 6/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.48 |
| ▸ | HRH2 | P25021 | 7/20 | 0.48 |
| ▸ | HRH1 | P35367 | 7/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6275066 | 0.95 | MAPT (0.57) | MMP2ALDH1A1MAPTMMP3MMP1 | |
| SCHEMBL25228734 | 0.91 | HDAC1 (0.56) | MMP2ALDH1A1MAPTMMP3MMP1 | |
| SCHEMBL25275009 | 0.91 | HDAC1 (0.56) | MMP2ALDH1A1MAPTMMP3MMP1 | |
| SCHEMBL25270396 | 0.91 | HDAC1 (0.56) | MMP2ALDH1A1MAPTMMP3MMP1 | |
| SCHEMBL6739953 | 0.91 | MAPT (0.53) | MMP2ALDH1A1MAPTMMP3MMP1 | |
| SCHEMBL2903095 | 0.87 | MAPT (0.51) | MMP2ALDH1A1MAPTMMP3MMP1 | |
| SCHEMBL7959199 | 0.87 | ALDH1A1 (0.51) | MMP2ALDH1A1MAPTMMP3MMP1 | |
| SCHEMBL7991604 | 0.81 | MMP2 (0.59) | MMP2ALDH1A1MAPTMMP3MMP1 | |
| SCHEMBL12751681 | 0.80 | ALDH1A1 (0.51) | MMP2ALDH1A1MAPTMMP3MMP1 | |
| SCHEMBL4510392 | 0.80 | MMP2 (0.48) | MMP2ALDH1A1MAPTMMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |