Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 4/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 2/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19630044 | 0.96 | GNAI3 (0.48) | GNAI3GNAO1GNAI1DRD3HTR1A | |
| SCHEMBL8975798 | 0.92 | MAOB (0.40) | KDM4E | |
| SCHEMBL9070252 | 0.88 | OPRM1 (0.44) | KDM4ELMNA | |
| SCHEMBL19634914 | 0.86 | GNAI3 (0.41) | GNAI3GNAO1GNAI1DRD3KDM4E | |
| SCHEMBL11809824 | 0.86 | TP53 (0.43) | GNAI3GNAO1GNAI1KDM4ES1PR1 | |
| SCHEMBL11870424 | 0.86 | OPRM1 (0.42) | LMNA | |
| SCHEMBL3411263 | 0.86 | OPRM1 (0.42) | LMNA | |
| SCHEMBL3589255 | 0.84 | KDM2B (0.39) | GNAI3GNAO1GNAI1KDM4ELMNA | |
| SCHEMBL19101360 | 0.82 | GNAI3 (0.38) | GNAI3GNAO1GNAI1LMNA | |
| SCHEMBL19481207 | 0.82 | GNAI3 (0.38) | GNAI3GNAO1GNAI1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313297-B1 | CATALYTIC ALKYLATION; BY-PRODUCT INHIBITION | AVENTIS RESEARCH & TECHNOLOGIES (DE) | 2001-11-06 | — | — | US | disclosed |
| EP-1047680-A2 | BASE-CATALYZED SYNTHESIS OF 1-ARYL-4-(ARYL ETHYL)PIPERAZINES FROM AROMATIC OLEFINS AND 1-ARYL PIPERAZINES | Aventis Research & Technologies GmbH & Co KG (DE) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999036412-A3 | BASE-CATALYZED SYNTHESIS OF 1-ARYL-4-(ARYL ETHYL)PIPERAZINES FROM AROMATIC OLEFINS AND 1-ARYL PIPERAZINES | HOECHST RES & TECH GMBH & CO (DE) | 1999-09-16 | — | — | WO | disclosed |
| WO-1999036412-A2 | BASE-CATALYZED SYNTHESIS OF 1-ARYL-4-(ARYL ETHYL)PIPERAZINES FROM AROMATIC OLEFINS AND 1-ARYL PIPERAZINES | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-07-22 | — | — | WO | disclosed |