Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.48 |
| ▸ | TUBB | P07437 | 5/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545626 | 0.87 | AKR1C3 (0.48) | AKR1C3AKR1C2TUBB4ATUBBTUBA3C | |
| SCHEMBL7256623 | 0.87 | BCAT2 (0.57) | AKR1C3AKR1C2KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL7499802 | 0.85 | ABCB1 (0.54) | AKR1C3AKR1C2TUBB4ATUBBTUBA3C | |
| SCHEMBL7614440 | 0.85 | TSHR (0.57) | AKR1C3AKR1C2TUBB4ATUBBTUBA3C | |
| SCHEMBL25295556 | 0.82 | ALDH1A1 (0.52) | KMT2ASMN1; SMN2RAB9AABCB1MEN1 | |
| SCHEMBL3787713 | 0.80 | AKR1C3 (0.60) | AKR1C3AKR1C2TUBB4ATUBBTUBA3C | |
| SCHEMBL7449464 | 0.79 | MEN1 (0.57) | AKR1C3AKR1C2TUBB4ATUBBTUBA3C | |
| SCHEMBL7546319 | 0.79 | TP53 (0.56) | AKR1C3AKR1C2TUBB4ATUBBTUBA3C | |
| SCHEMBL7613027 | 0.79 | AKR1C3 (0.52) | AKR1C3AKR1C2TUBB4ATUBBTUBA3C | |
| SCHEMBL7762502 | 0.79 | BCAT2 (0.56) | KMT2ASMN1; SMN2RAB9AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258843-B1 | DRUGS AS ENZYME INHIBITORS | NOVARTIS AG (CH) | 2001-07-10 | — | — | US | claimed |