Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 11/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989975 | 0.91 | DHODH (0.61) | DHODHMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7977709 | 0.89 | DHODH (0.58) | DHODHMEN1KMT2APRMT5CHEK2 | |
| SCHEMBL7977622 | 0.89 | DHODH (0.58) | DHODHMEN1KMT2APRMT5CHEK2 | |
| SCHEMBL7977737 | 0.88 | PRMT5 (0.57) | DHODHMAPTMEN1KMT2AKDM4E | |
| SCHEMBL7989535 | 0.82 | MAPK1 (0.61) | DHODHMAPTMEN1KMT2AKDM4E | |
| SCHEMBL15075613 | 0.81 | MAPK13 (0.63) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7995495 | 0.81 | MAPK13 (0.63) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7988588 | 0.81 | PRMT5 (0.58) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6681257 | 0.80 | PRMT5 (0.53) | DHODHMAPTMEN1KMT2AKDM4E | |
| SCHEMBL7977899 | 0.79 | PRMT5 (0.56) | DHODHMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |