Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 8/20 | 0.56 |
| ▸ | DHODH | Q02127 | 4/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 2/20 | 0.49 |
| ▸ | GABRD | O14764 | 2/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.49 |
| ▸ | GABRE | P78334 | 2/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988588 | 0.92 | PRMT5 (0.58) | PRMT5DHODHGABRA1GABRG2GABRB3 | |
| SCHEMBL7977737 | 0.91 | PRMT5 (0.57) | PRMT5DHODHGABRA1GABRG2GABRB3 | |
| SCHEMBL7988443 | 0.90 | PRMT5 (0.56) | PRMT5DHODHGABRA1GABRG2GABRB3 | |
| SCHEMBL7977622 | 0.87 | DHODH (0.58) | PRMT5DHODHMMP13CHEK2MEN1 | |
| SCHEMBL7988623 | 0.84 | ALOX5 (0.52) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28582964 | 0.81 | TARBP2 (0.54) | GABRA2ALOX5GABRB2ALDH1A1MAPT | |
| SCHEMBL7989975 | 0.81 | DHODH (0.61) | PRMT5DHODHALDH1A1HPGDCHEK2 | |
| SCHEMBL7992311 | 0.80 | ALOX5 (0.54) | GABRA2ALOX5GABRB2ALDH1A1MAPT | |
| SCHEMBL7991836 | 0.79 | DHODH (0.58) | PRMT5DHODHALDH1A1MAPTHPGD | |
| SCHEMBL7989451 | 0.79 | ALOX5 (0.58) | GABRA2ALOX5GABRB2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |