Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.61 |
| ▸ | PRMT5 | O14744 | 10/20 | 0.54 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991836 | 0.91 | DHODH (0.58) | DHODHPRMT5CHEK2MEN1KMT2A | |
| SCHEMBL7988588 | 0.89 | PRMT5 (0.58) | DHODHPRMT5CHEK2MEN1KMT2A | |
| SCHEMBL7977622 | 0.89 | DHODH (0.58) | DHODHPRMT5CHEK2MEN1KMT2A | |
| SCHEMBL7977709 | 0.89 | DHODH (0.58) | DHODHPRMT5CHEK2MEN1KMT2A | |
| SCHEMBL7978027 | 0.84 | KDM4E (0.67) | DHODHMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7989548 | 0.82 | MEN1 (0.55) | DHODHPRMT5MEN1KMT2AKDM4E | |
| SCHEMBL7977737 | 0.82 | PRMT5 (0.57) | DHODHPRMT5CHEK2MEN1KMT2A | |
| SCHEMBL7977899 | 0.81 | PRMT5 (0.56) | DHODHPRMT5CHEK2MEN1KMT2A | |
| SCHEMBL7988443 | 0.81 | PRMT5 (0.56) | DHODHPRMT5CHEK2MEN1KMT2A | |
| SCHEMBL7977763 | 0.78 | CTRC (0.53) | DHODHCHEK2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |