Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991934 | 0.90 | MAPT (0.52) | MAPTALDH1A1MMP13MMP2MMP9 | |
| SCHEMBL7995168 | 0.89 | MAPT (0.51) | MAPTALDH1A1MMP13MMP2MMP9 | |
| SCHEMBL7988260 | 0.89 | MAPT (0.51) | MAPTALDH1A1MMP13MMP2MMP9 | |
| SCHEMBL7992254 | 0.89 | MAPT (0.54) | MAPTALDH1A1MMP13MMP2MMP9 | |
| SCHEMBL7991879 | 0.85 | MAPT (0.51) | MAPTALDH1A1MMP13MMP2MMP9 | |
| SCHEMBL7978081 | 0.84 | MAPT (0.52) | MAPTALDH1A1MMP13MMP2MMP9 | |
| SCHEMBL7989862 | 0.83 | AR (0.54) | MAPTALDH1A1MMP2MMP9MMP8 | |
| SCHEMBL28914603 | 0.83 | AR (0.54) | MAPTALDH1A1MMP2MMP9MMP8 | |
| SCHEMBL7992024 | 0.83 | AR (0.58) | MAPTMMP13MMP2MMP9MMP8 | |
| SCHEMBL7988441 | 0.80 | AR (0.55) | MAPTALDH1A1MMP13MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |