Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988461 | 0.92 | F2 (0.50) | MAPTPIN1ALDH1A1KDM4EF2 | |
| SCHEMBL7995168 | 0.92 | MAPT (0.51) | MAPTALDH1A1F2PLAUELANE | |
| SCHEMBL7989208 | 0.87 | PIN1 (0.61) | MAPTPIN1ALDH1A1HCRTR1ADORA2A | |
| SCHEMBL7988260 | 0.86 | MAPT (0.51) | MAPTALDH1A1HCRTR1MEN1KMT2A | |
| SCHEMBL7991863 | 0.85 | MAPT (0.52) | MAPTALDH1A1KDM4EHCRTR1MEN1 | |
| SCHEMBL7991934 | 0.85 | MAPT (0.52) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL7988102 | 0.81 | MAPT (0.54) | MAPTMEN1KMT2ARAB9AMMP2 | |
| SCHEMBL7989904 | 0.79 | MEN1 (0.54) | MAPTPIN1ALDH1A1KDM4EPLAU | |
| SCHEMBL7988557 | 0.79 | PIN1 (0.58) | MAPTPIN1ALDH1A1KDM4EMEN1 | |
| SCHEMBL7991730 | 0.79 | MEN1 (0.56) | MAPTALDH1A1KDM4EPLAUHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |