SCHEMBL7991930

SCHEMBL7991930

CON=C(C(=S)OC)c1ccccc1CON=C(C)c1cccc(C(F)(F)F)c1

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 6/20 0.49
NPSR1 Q6W5P4 2/20 0.44
GAA P10253 1/20 0.43
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
RXFP1 Q9HBX9 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363702 0.88 HIF1A (0.64) HIF1ANPSR1GAAKMT2AMEN1
SCHEMBL7973685 0.88 HIF1A (0.49) HIF1ANPSR1GAAKMT2AMEN1
SCHEMBL9880011 0.88 HIF1A (0.64) HIF1ANPSR1GAAKMT2AMEN1
SCHEMBL28465127 0.88 HIF1A (0.64) HIF1ANPSR1GAAKMT2AMEN1
SCHEMBL7960472 0.88 HIF1A (0.64) HIF1ANPSR1GAAKMT2AMEN1
SCHEMBL2321633 0.88 HIF1A (0.64) HIF1ANPSR1GAAKMT2AMEN1
SCHEMBL19148 0.88 HIF1A (0.64) HIF1ANPSR1GAAKMT2AMEN1
SCHEMBL12635931 0.88 HIF1A (0.64) HIF1ANPSR1GAAKMT2AMEN1
SCHEMBL29368184 0.88 HIF1A (0.64) HIF1ANPSR1GAAKMT2AMEN1
SCHEMBL297033 0.88 HIF1A (0.64) HIF1ANPSR1GAAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6177463-B1 FUNGICIDES; BACTERICIDES; MICROBIOCIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-01-23 US disclosed