Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 5/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988263 | 0.87 | CHEK2 (0.44) | NPBWR1MAPTALDH1A1HTTRAB9A | |
| SCHEMBL7995651 | 0.86 | SIRT2 (0.41) | MAPTMMP2MMP9MEN1TP53 | |
| SCHEMBL7995167 | 0.84 | MAPK14 (0.54) | NPBWR1MAPTALDH1A1HTTRAB9A | |
| SCHEMBL7977715 | 0.79 | MAPT (0.51) | MAPTALDH1A1HTTRAB9AL3MBTL1 | |
| SCHEMBL7992024 | 0.78 | AR (0.58) | NPBWR1ARMAPTHTTRAB9A | |
| SCHEMBL7988289 | 0.77 | GCGR (0.39) | MAPTTP53ALOX5 | |
| SCHEMBL7977722 | 0.76 | NPBWR1 (0.53) | NPBWR1ARMAPTHTTRAB9A | |
| SCHEMBL7988441 | 0.75 | AR (0.55) | NPBWR1ARMAPTALDH1A1HTT | |
| SCHEMBL28914603 | 0.74 | AR (0.54) | NPBWR1ARMAPTALDH1A1HTT | |
| SCHEMBL7989862 | 0.74 | AR (0.54) | NPBWR1ARMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |