Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.54 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991975 | 0.85 | MAPK14 (0.49) | MAPK14ALOX5RAB9AMEN1KMT2A | |
| SCHEMBL7991767 | 0.84 | MAPK11 (0.57) | MAPK14ALOX5MAPTMEN1LMNA | |
| SCHEMBL7995659 | 0.84 | GCGR (0.54) | MAPK14ALOX5MAPK13MAPK12MAPK11 | |
| SCHEMBL7977727 | 0.84 | RAF1 (0.55) | MAPK14ALOX5LMNAMAPK13MAPK12 | |
| SCHEMBL7992017 | 0.84 | NPBWR1 (0.42) | MAPK14ALOX5MAPTRAB9AMEN1 | |
| SCHEMBL7989693 | 0.83 | MAPK14 (0.54) | MAPK14ALOX5MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7977803 | 0.83 | GCGR (0.53) | MAPK14ALOX5MAPK13MAPK12MAPK11 | |
| SCHEMBL7991834 | 0.83 | MAPK14 (0.61) | MAPK14ALOX5MAPTRAB9AMEN1 | |
| SCHEMBL7992024 | 0.78 | AR (0.58) | MAPK14MAPTRAB9AMEN1KMT2A | |
| SCHEMBL7977722 | 0.77 | NPBWR1 (0.53) | MAPK14MAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |