Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2311217 | 0.84 | CYP2C19 (0.46) | KDM1AMAOBSLC6A3CYP2C19 | |
| SCHEMBL7447763 | 0.82 | SIGMAR1 (0.53) | KDM1AMAOBBCHE | |
| SCHEMBL378027 | 0.77 | PDPK1 (0.50) | KDM1AMAOBKDM4EPDPK1SLC6A3 | |
| SCHEMBL2718512 | 0.76 | MAOB (0.55) | KDM1AMAOBMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL3930720 | 0.76 | PDPK1 (0.48) | KDM1AMAOBKDM4EPDPK1SLC6A3 | |
| SCHEMBL6657646 | 0.76 | PDPK1 (0.48) | KDM1AMAOBKDM4EPDPK1SLC6A3 | |
| SCHEMBL7617248 | 0.76 | PDPK1 (0.48) | KDM1AMAOBKDM4EPDPK1SLC6A3 | |
| Hydrochloric Acid SCHEMBL31038658 | 0.73 | MEN1 (0.70) | KDM4EMEN1KMT2ATDP1BCHE | |
| SCHEMBL1039947 | 0.73 | — | — | |
| Benzene SCHEMBL11697595 | 0.73 | MEN1 (0.78) | KDM4EMEN1KMT2ATDP1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416948-B1 | INDACENE BEARING SULFONYLUREAS AS ANTI-INFLAMMATORY AGENTS | UNIV QUEENSLAND (AU) | 2024-07-24 | — | — | EP | claimed |
| EP-0571471-A1 | 5-HETEROYL INDOLE DERIVATIVES. | PFIZER (US) | 1993-12-01 | — | — | EP | claimed |
| US-6277871-B1 | ANTICANCER AGENTS | ABBOTT LABORATORIES | 2001-08-21 | — | — | US | disclosed |