Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1678642 | 0.74 | HPGD (0.59) | SIGMAR1CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL7724183 | 0.71 | SIGMAR1 (0.55) | SIGMAR1PRMT3 | |
| SCHEMBL10865787 | 0.71 | MAOB (0.41) | PDE10ANPC1RAB9A | |
| SCHEMBL25168672 | 0.71 | TDP1 (0.36) | PDE10ANPC1RAB9A | |
| SCHEMBL716430 | 0.69 | SIGMAR1 (0.48) | SIGMAR1CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL23023177 | 0.67 | SIGMAR1 (0.77) | SIGMAR1CHRM2NPC1RAB9A | |
| SCHEMBL23023029 | 0.67 | SIGMAR1 (0.77) | SIGMAR1CHRM2NPC1RAB9A | |
| SCHEMBL13212565 | 0.66 | PDE10A (0.35) | PDE10ANPC1RAB9A | |
| SCHEMBL23022917 | 0.66 | SIGMAR1 (0.49) | SIGMAR1CHRM2CHRM1CHRM3NPC1 | |
| SCHEMBL1347800 | 0.66 | CXCR4 (0.47) | SIGMAR1NPC1RAB9ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277871-B1 | ANTICANCER AGENTS | ABBOTT LABORATORIES | 2001-08-21 | — | — | US | disclosed |