Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ADH1B | P00325 | 1/20 | 0.42 |
| ▸ | ADH1C | P00326 | 1/20 | 0.42 |
| ▸ | ADH1A | P07327 | 1/20 | 0.42 |
| ▸ | ADH4 | P08319 | 1/20 | 0.42 |
| ▸ | ADH7 | P40394 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660951 | 0.88 | CYP1A2 (0.54) | SIGMAR1EPHX1CYP1A2BCHEADH1B | |
| SCHEMBL8944543 | 0.88 | CYP1A2 (0.54) | SIGMAR1EPHX1CYP1A2BCHEADH1B | |
| SCHEMBL1615543 | 0.88 | SIGMAR1 (0.56) | SIGMAR1EPHX1CYP1A2BCHECHRM2 | |
| SCHEMBL4470765 | 0.88 | SIGMAR1 (0.41) | SIGMAR1EPHX1CYP1A2BCHEADH1B | |
| SCHEMBL630159 | 0.88 | SIGMAR1 (0.41) | SIGMAR1EPHX1CYP1A2BCHEADH1B | |
| SCHEMBL19841305 | 0.88 | SIGMAR1 (0.41) | SIGMAR1EPHX1CYP1A2BCHEADH1B | |
| SCHEMBL3681785 | 0.88 | EPHX1 (0.44) | SIGMAR1EPHX1CYP1A2BCHEADH1B | |
| SCHEMBL24500037 | 0.87 | ADH1B (0.48) | SIGMAR1EPHX1CYP1A2ADH1BADH1C | |
| SCHEMBL14606660 | 0.87 | ADH1B (0.48) | SIGMAR1EPHX1CYP1A2ADH1BADH1C | |
| Hydrochloric Acid SCHEMBL7862878 | 0.86 | SIGMAR1 (0.39) | SIGMAR1EPHX1CYP1A2BCHEADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076498-B1 | PREPARATION OF AZOXYSTROBIN | SYNGENTA LTD (GB) | 2015-02-25 | — | — | EP | disclosed |
| US-8552185-B2 | Preparation of azoxystrobin | SYNGENTA LIMITED (GB) | 2013-10-08 | — | — | US | disclosed |
| US-8124761-B2 | Coupling of methyl (E)-2-{2-[6-chloropyrimidin-4-yloxy]phenyl}-3-methoxyacrylate with 2-cyanophenyl in DMF with 2 mol % DABCO; significantly smaller amounts of this relatively expensive catalyst may be used without compromising the yield | SYNGENTA LIMITED (GB) | 2012-02-28 | — | — | US | disclosed |
| US-20100036124-A1 | PREPARATION OF AZOXYSTROBIN | SYNGENTA LIMITED (GB) | 2010-02-11 | — | — | US | disclosed |
| US-20080214587-A1 | Processes For the Preparation of Azoxystrobin Using Dabco as a Catalyst and Novel Intermediates Used in the Processes | SYNGENTA CROP PROTECTION, INC. (US) | 2008-09-04 | — | — | US | disclosed |
| US-5177069-A | Cholecystokinin inhibitor, pancreatic antisecretory agent | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0433064-A1 | Naphthylsulfonylalkanoic acid compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1991-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036124-A1 | PREPARATION OF AZOXYSTROBIN | CYP51A1, CYP1B1, CYP2D6 | SIGMAR1 2982/4885EPHX1 1598/4885CYP1A2 4/4885 |
| US-20080214587-A1 | Processes For the Preparation of Azoxystrobin Using Dabco as a Catalyst and Novel Intermediates Used in the Processes | DDT, AOC3, DAO | SIGMAR1 2893/4885EPHX1 1790/4885CYP1A2 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.