Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.68 |
| ▸ | MAPK11 | Q15759 | 14/20 | 0.68 |
| ▸ | MAPK13 | O15264 | 13/20 | 0.68 |
| ▸ | MAPK12 | P53778 | 13/20 | 0.68 |
| ▸ | ALOX5 | P09917 | 11/20 | 0.68 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.68 |
| ▸ | GCGR | P47871 | 11/20 | 0.62 |
| ▸ | CSNK1A1 | P48729 | 4/20 | 0.62 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.62 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.62 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.62 |
| ▸ | FRK | P42685 | 3/20 | 0.62 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.62 |
| ▸ | GSK3B | P49841 | 3/20 | 0.62 |
| ▸ | PTK6 | Q13882 | 3/20 | 0.62 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.62 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992089 | 0.87 | MAPK14 (0.62) | MAPK14MAPK11MAPK13MAPK12ALOX5 | |
| SCHEMBL7995288 | 0.86 | MAPK13 (0.52) | MAPK14MAPK11MAPK13MAPK12ALOX5 | |
| SCHEMBL7989925 | 0.86 | MAPK14 (0.62) | MAPK14MAPK11MAPK13MAPK12ALOX5 | |
| SCHEMBL7992039 | 0.86 | MAPK14 (0.56) | MAPK14MAPK11MAPK13MAPK12ALOX5 | |
| SCHEMBL7977738 | 0.86 | MAPK14 (0.56) | MAPK14MAPK11MAPK13MAPK12ALOX5 | |
| SCHEMBL15075613 | 0.82 | MAPK13 (0.63) | MAPK14MAPK11MAPK13MAPK12ALOX5 | |
| SCHEMBL7995495 | 0.82 | MAPK13 (0.63) | MAPK14MAPK11MAPK13MAPK12ALOX5 | |
| SCHEMBL7991943 | 0.82 | MAPK14 (0.58) | MAPK14MAPK11MAPK13MAPK12ALOX5 | |
| SCHEMBL413667 | 0.81 | MAPK14 (1.00) | MAPK14MAPK11MAPK13MAPK12ALOX5 | |
| SCHEMBL7988678 | 0.81 | MAPK14 (0.61) | MAPK14MAPK11MAPK13MAPK12ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |