Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 8/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.52 |
| ▸ | RAF1 | P04049 | 2/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 6/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | FRK | P42685 | 2/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992002 | 0.90 | MAPK13 (0.60) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL6366542 | 0.89 | MAPK13 (0.59) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL7977996 | 0.88 | TRPV1 (0.49) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL7988191 | 0.88 | NPBWR1 (0.53) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL7995390 | 0.88 | MAPK14 (0.48) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL7992159 | 0.86 | MAPK14 (0.68) | MAPK13MAPK12MAPK11MAPK14ALOX5 | |
| SCHEMBL7989517 | 0.84 | MAPT (0.49) | MAPK13MAPK12MAPK11MAPK14ALOX5 | |
| SCHEMBL7989451 | 0.82 | ALOX5 (0.58) | MAPK13MAPK12MAPK11MAPK14ALOX5 | |
| SCHEMBL6631782 | 0.80 | PIN1 (0.67) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL14705957 | 0.80 | ESR1 (0.47) | MAPK13MAPK12MAPK11MAPK14ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |