Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.62 |
| ▸ | MAPK13 | O15264 | 12/20 | 0.62 |
| ▸ | MAPK12 | P53778 | 12/20 | 0.62 |
| ▸ | MAPK11 | Q15759 | 12/20 | 0.62 |
| ▸ | GCGR | P47871 | 9/20 | 0.62 |
| ▸ | RAF1 | P04049 | 5/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992089 | 0.87 | MAPK14 (0.62) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL7977738 | 0.86 | MAPK14 (0.56) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL7992039 | 0.86 | MAPK14 (0.56) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL7992159 | 0.86 | MAPK14 (0.68) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL8312008 | 0.85 | MAPK14 (0.61) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL7995390 | 0.85 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL7991890 | 0.83 | BRAF (0.48) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL7995219 | 0.82 | RHEB (0.48) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL7995495 | 0.82 | MAPK13 (0.63) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL15075613 | 0.82 | MAPK13 (0.63) | MAPK14MAPK13MAPK12MAPK11GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |