Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.68 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.65 |
| ▸ | RAF1 | P04049 | 3/20 | 0.65 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.65 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.65 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | CDC7 | O00311 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.48 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989739 | 0.85 | MAPK14 (0.56) | PIN1MAPK14RAF1MAPK13MAPK12 | |
| SCHEMBL15075613 | 0.85 | MAPK13 (0.63) | PIN1MAPK14RAF1MAPK13MAPK12 | |
| SCHEMBL7995495 | 0.85 | MAPK13 (0.63) | PIN1MAPK14RAF1MAPK13MAPK12 | |
| SCHEMBL7992089 | 0.82 | MAPK14 (0.62) | PIN1MAPK14RAF1MAPK13MAPK12 | |
| SCHEMBL6469927 | 0.81 | MAPK14 (0.90) | MAPK14RAF1MAPK13MAPK12MAPK11 | |
| SCHEMBL7989208 | 0.81 | PIN1 (0.61) | PIN1PARP1HCRTR1MAPTCYP1A2 | |
| Hydrochloric Acid SCHEMBL7988593 | 0.79 | MAPK1 (0.50) | PIN1MAPK14RAF1MAPK13MAPK12 | |
| SCHEMBL7988557 | 0.79 | PIN1 (0.58) | PIN1MAPK14RAF1MAPK13MAPK12 | |
| SCHEMBL28580042 | 0.78 | PIN1 (0.60) | PIN1MAPK14RAF1MAPK13MAPK12 | |
| SCHEMBL7989904 | 0.77 | MEN1 (0.54) | PIN1ALOX5HCRTR1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |