Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19287695 | 0.86 | KDM4E (0.36) | KDM4EIRAK4CHRM4MEN1 | |
| SCHEMBL9061374 | 0.78 | KDM4E (0.37) | KDM4EIRAK4CHRM4MEN1 | |
| SCHEMBL7970268 | 0.77 | KDM4E (0.33) | KDM4ECHRM4 | |
| SCHEMBL8485612 | 0.76 | KDM4E (0.38) | KDM4EIRAK4CHRM4MEN1 | |
| SCHEMBL8767585 | 0.76 | KDM4E (0.38) | KDM4EIRAK4CHRM4MEN1 | |
| SCHEMBL7977980 | 0.75 | TP53 (0.33) | KDM4EIRAK4CHRM4 | |
| SCHEMBL8486785 | 0.75 | BTK (0.42) | KDM4EIRAK4 | |
| SCHEMBL8487365 | 0.75 | BTK (0.42) | KDM4EIRAK4 | |
| SCHEMBL7828462 | 0.75 | CYP1A2 (0.43) | KDM4EIRAK4MEN1 | |
| SCHEMBL8490025 | 0.75 | IRAK4 (0.45) | KDM4EIRAK4CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281221-B1 | Substituted 1,3-dioxan-5-ylamino-hererocyclic compounds, processes for their preparation and their use as pest control compositions | HOECHST SCERING AGREVO GMBH (DE) | 2001-08-28 | — | — | US | disclosed |
| EP-0836603-A1 | SUBSTITUTED 1,3-DIOXAN-5-YLAMINO HETEROCYCLIC COMPOUNDS, METHODS FOR PREPARING THEM AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002264-A1 | SUBSTITUTED 1,3-DIOXAN-5-YLAMINO HETEROCYCLIC COMPOUNDS, METHODS FOR PREPARING THEM AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1997-01-23 | — | — | WO | disclosed |