SCHEMBL7992283

SCHEMBL7992283

O=C(C(=O)N1CCC[C@H]1C(=O)OCCCc1ccccc1)c1ccco1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 18/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8810826 1.00 FKBP1A (0.68) FKBP1A
SCHEMBL7919868 0.87 FKBP1A (0.76) FKBP1A
SCHEMBL5966005 0.84 FKBP1A (0.81) FKBP1A
SCHEMBL7412937 0.82 FKBP1A (0.66) FKBP1A
SCHEMBL8099641 0.81 FKBP1A (1.00) FKBP1A
SCHEMBL14407800 0.79 ACE (0.52)
SCHEMBL3144701 0.79 ACE (0.52)
SCHEMBL29692766 0.79 FKBP1A (0.69) FKBP1A
SCHEMBL5966071 0.79 FKBP1A (1.00) FKBP1A
SCHEMBL3426604 0.78 FKBP1A (1.00) FKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6291510-B1 N-LINKED 1,2-DIKETO PROLYL ESTER COMPOUND OR A N-LINKED 1,2-DIKETO PROLYL AMIDE COMPOUND, WHEREIN SAID ESTER COMPOUND OR SAID AMIDE COMPOUND IS NON-IMMUNOSUPPRESSIVE. GPI NIL HOLDINGS, INC. 2001-09-18 US disclosed