Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.35 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.34 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6432078 | 0.87 | NR1I3 (0.47) | SRD5A2GRIN1GRIN2BAKR1B10AKR1B1 | |
| SCHEMBL17065133 | 0.80 | AKR1B10 (0.58) | SRD5A2GRIN1GRIN2BAKR1B10AKR1B1 | |
| SCHEMBL8964927 | 0.79 | CYP19A1 (0.49) | SRD5A2AKR1B10AKR1B1GPBAR1ALDH1A1 | |
| SCHEMBL8964931 | 0.79 | CYP19A1 (0.49) | SRD5A2AKR1B10AKR1B1GPBAR1ALDH1A1 | |
| SCHEMBL3361092 | 0.79 | SRD5A2 (0.40) | SRD5A2AKR1B10AKR1B1GPBAR1ALDH1A1 | |
| SCHEMBL9706991 | 0.78 | CYP17A1 (0.46) | SRD5A2AKR1B10AKR1B1GPBAR1ALDH1A1 | |
| SCHEMBL5004417 | 0.72 | CYP19A1 (0.52) | GRIN1GRIN2BAKR1B10AKR1B1GPBAR1 | |
| SCHEMBL4292109 | 0.71 | OSBP (0.52) | SRD5A2 | |
| SCHEMBL9293470 | 0.69 | GRIN1 (0.50) | SRD5A2GRIN1GRIN2BNR1I3MEN1 | |
| SCHEMBL9822483 | 0.69 | SRD5A2 (0.74) | SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274118-B1 | INJECTING PATIENT HAVING ENDOCRINE CANCER IN NON-PROSTATIC TISSUE WITH BIOLOGICAL BINDING UNITS WHICH BIND TO PROSTATE SPECIFIC ANTIGEN PRODUCED BY NON-PROSTATIC TISSUE | NORDION INTERNATIONAL INC. (CA) | 2001-08-14 | — | — | US | disclosed |
| WO-1995002424-A1 | LOCALIZATION AND THERAPY OF NON-PROSTATIC ENDOCRINE CANCER WITH AGENTS DIRECTED AGAINST PROSTATE SPECIFIC ANTIGEN | NORDION INTERNATIONAL INC. (CA) | 1995-01-26 | — | — | WO | disclosed |