Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84448 | 0.84 | TRPA1 (0.56) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL17767222 | 0.80 | PDE2A (0.58) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL20811584 | 0.80 | PDE2A (0.58) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL17769044 | 0.80 | PDE2A (0.58) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL18103172 | 0.80 | TRPA1 (0.42) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL13345087 | 0.80 | TRPA1 (0.47) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| Ammonia Solution, Strong SCHEMBL7989997 | 0.79 | CES2 (0.44) | SLC6A2PDE2A | |
| SCHEMBL8981744 | 0.79 | TRPA1 (0.40) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| Hydrochloric Acid SCHEMBL20790467 | 0.78 | PDE2A (0.56) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| Hydrochloric Acid SCHEMBL20790469 | 0.78 | PDE2A (0.56) | TRPA1LMNACHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277851-B1 | ORALLY ADMINISTERED TRYPSIN-RELATED SERINE PROTEASE INHIBITORS; ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 2001-08-21 | — | — | US | disclosed |