Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.39 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL799332 | 0.84 | ALDH1A1 (0.37) | PI4KBPIK3C2GPI4KAMAPTSMN1; SMN2 | |
| SCHEMBL1236720 | 0.80 | PIK3CG (0.47) | PI4KBPIK3C2GPIK3CDPIK3CAPIK3CG | |
| SCHEMBL172000 | 0.79 | ALDH1A1 (0.38) | PI4KBPI4KAMAPTLMNAKDM4E | |
| SCHEMBL1237551 | 0.75 | PIK3CG (0.46) | PI4KBPIK3C2GPIK3CDPIK3CAPIK3CG | |
| SCHEMBL799251 | 0.73 | PIK3CD (0.62) | PI4KBSMN1; SMN2RAB9AXIAPPIK3CD | |
| SCHEMBL1236616 | 0.73 | PIK3CG (0.45) | PI4KBPIK3C2GPIK3CDPIK3CAPIK3CG | |
| SCHEMBL1236893 | 0.72 | PIK3CG (0.53) | PI4KBPI4KAPIK3CDPIK3CAPIK3CG | |
| SCHEMBL1235188 | 0.72 | PIK3CG (0.51) | PI4KBPIK3C2GLMNAPIK3CDPIK3CA | |
| SCHEMBL1237555 | 0.72 | PIK3CG (0.46) | PI4KBPIK3C2GPIK3CDPIK3CAPIK3CG | |
| SCHEMBL1237271 | 0.71 | MAPT (0.39) | PIK3C2GMAPTSMN1; SMN2LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071475-A1 | UREA DERIVATIVES HAVING PI3K-INHIBITING ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2012-03-22 | — | — | US | disclosed |
| US-20120071475-A1 | UREA DERIVATIVES HAVING PI3K-INHIBITING ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071475-A1 | UREA DERIVATIVES HAVING PI3K-INHIBITING ACTIVITY | MTOR, STAT3, SLC14A1 | PI4KB 28/4885PIK3C2G 71/4885PI4KA 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.