Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.56 |
| ▸ | XDH | P47989 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996126 | 0.83 | GSK3B (0.63) | GSK3BXDHCDC7BACE1 | |
| SCHEMBL7992743 | 0.81 | GSK3B (0.56) | GSK3BXDHCDC7 | |
| SCHEMBL7978702 | 0.79 | GSK3B (0.59) | GSK3BXDH | |
| SCHEMBL7990818 | 0.78 | GSK3B (0.50) | GSK3BXDH | |
| SCHEMBL5379886 | 0.75 | GSK3B (0.58) | GSK3BXDHCDC7DBF4 | |
| SCHEMBL7993214 | 0.73 | GSK3B (0.48) | GSK3BXDH | |
| SCHEMBL5391514 | 0.73 | GSK3B (0.60) | GSK3BXDHCDC7 | |
| SCHEMBL5198148 | 0.73 | GSK3B (0.52) | GSK3BXDH | |
| SCHEMBL5383563 | 0.73 | GSK3B (0.70) | GSK3BCDC7 | |
| SCHEMBL5390685 | 0.72 | GSK3B (1.00) | GSK3BXDHCDC7BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070727-A1 | 2-(ARYLALKYLAMINO)PYRIMIDONE DERIVATIVES AND 2-(HETEROARYLALKYLAMINO)PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | disclosed |