Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.59 |
| ▸ | XDH | P47989 | 3/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996126 | 0.96 | GSK3B (0.63) | GSK3BXDH | |
| SCHEMBL7978487 | 0.82 | GSK3B (0.48) | GSK3B | |
| SCHEMBL7990818 | 0.80 | GSK3B (0.50) | GSK3BXDH | |
| SCHEMBL7992592 | 0.79 | GSK3B (0.56) | GSK3BXDH | |
| SCHEMBL7992743 | 0.77 | GSK3B (0.56) | GSK3BXDH | |
| SCHEMBL5387930 | 0.75 | GSK3B (1.00) | GSK3BXDHGPR84 | |
| SCHEMBL5379886 | 0.75 | GSK3B (0.58) | GSK3BXDH | |
| SCHEMBL5104864 | 0.74 | GSK3B (0.87) | GSK3B | |
| SCHEMBL2403418 | 0.73 | GSK3B (1.00) | GSK3B | |
| SCHEMBL5391514 | 0.73 | GSK3B (0.60) | GSK3BXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070727-A1 | 2-(ARYLALKYLAMINO)PYRIMIDONE DERIVATIVES AND 2-(HETEROARYLALKYLAMINO)PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | disclosed |