Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1351234 | 0.86 | CYP1A2 (0.48) | POLBSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL3069772 | 0.84 | CYP1A2 (0.44) | ALOX5APFEN1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL10474120 | 0.79 | CYP1A2 (0.41) | POLBCYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8098004 | 0.78 | MEN1 (0.38) | POLBSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL5597411 | 0.77 | POLB (0.43) | POLBALOX5APFEN1SLC6A2SLC6A4 | |
| SCHEMBL20734748 | 0.77 | ALOX5AP (0.43) | ALOX5APFEN1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL16943934 | 0.77 | GABRA1 (0.41) | ALOX5APFEN1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL10954298 | 0.77 | CYP1A2 (0.63) | POLBSLC6A4SLC6A3CYP3A4CYP1A2 | |
| SCHEMBL28861078 | 0.77 | POLB (0.46) | POLBSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL29565534 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009156072-A1 | SUBSTITUTED 7-SULFANYLMETHYL, 7-SULFINYLMETHYL AND 7-SULFONYLMETHYL INDOLES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-12-30 | — | — | WO | disclosed |