SCHEMBL7992848

SCHEMBL7992848

COC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(OC)cc1

nearest known ligand 0.70

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 4/20 0.70
MMP3 P08254 3/20 0.70
MMP7 P09237 2/20 0.70
MMP13 P45452 1/20 0.70
HCRTR1 O43613 11/20 0.69
HCRTR2 O43614 11/20 0.69
CYP3A4 P08684 2/20 0.66
ALDH1A1 P00352 2/20 0.65
GAA P10253 1/20 0.65
TSHR P16473 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
MAPK1 P28482 1/20 0.65
ADAM17 P78536 1/20 0.64
MMP9 P14780 1/20 0.63
PKM P14618 1/20 0.62
HTT P42858 1/20 0.61
CYP2C19 P33261 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24979959 0.96 MMP1 (0.65) MMP1MMP3MMP7MMP13HCRTR1
SCHEMBL8209517 0.96 MMP1 (0.76) MMP1MMP3MMP7MMP13HCRTR1
SCHEMBL6229896 0.93 MMP1 (0.69) MMP1MMP3MMP7MMP13HCRTR1
SCHEMBL20291410 0.92 ALDH1A1 (0.69) MMP1MMP3MMP7MMP13HCRTR1
SCHEMBL5885922 0.88 ALDH1A1 (0.70) HCRTR1HCRTR2CYP3A4ALDH1A1GAA
SCHEMBL2705860 0.88 MMP1 (0.67) MMP1MMP3MMP7MMP13HCRTR1
SCHEMBL2706480 0.88 MMP1 (0.67) MMP1MMP3MMP7MMP13HCRTR1
SCHEMBL2705855 0.88 MMP1 (0.67) MMP1MMP3MMP7MMP13HCRTR1
SCHEMBL5885924 0.88 ALDH1A1 (0.70) HCRTR1HCRTR2CYP3A4ALDH1A1GAA
SCHEMBL7349862 0.87 MMP1 (0.91) MMP1MMP3MMP7MMP13HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025124698-A1 ARYL SULFONE AND SULFANONE DERIVATIVES AS OREXIN RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2025-06-19 WO disclosed
EP-0845987-A4 C-PROTEINASE INHIBITORS FOR THE TREATMENT OF DISORDERS RELATED TO THE OVERPRODUCTION OF COLLAGEN FIBROGEN INC (US) 2000-05-24 EP disclosed
CN-1198096-A C-proteinase inhibitor for treatment of disorders related to overproduction of collagen FIBROGEN INC (US) 1998-11-04 CN disclosed
EP-0845987-A1 C-PROTEINASE INHIBITORS FOR THE TREATMENT OF DISORDERS RELATED TO THE OVERPRODUCTION OF COLLAGEN FIBROGEN, INC. (US) 1998-06-10 EP disclosed
WO-1997005865-A1 C-PROTEINASE INHIBITORS FOR THE TREATMENT OF DISORDERS RELATED TO THE OVERPRODUCTION OF COLLAGEN FIBROGEN, INC. (US) 1997-02-20 WO disclosed