Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.49 |
| ▸ | HMGB1 | P09429 | 3/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.44 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467709 | 0.90 | HMGB1 (0.56) | HPGDALDH1A1HSD17B10PTPN1PTPN2 | |
| SCHEMBL1161183 | 0.88 | HMGB1 (0.57) | HPGDALDH1A1HSD17B10PTPN1PTPN2 | |
| SCHEMBL29697016 | 0.80 | HMGB1 (0.67) | HPGDALDH1A1HSD17B10PTPN1PTPN2 | |
| SCHEMBL633197 | 0.80 | HMGB1 (0.67) | HPGDALDH1A1HSD17B10PTPN1PTPN2 | |
| SCHEMBL11327561 | 0.79 | HMGB1 (0.54) | HPGDALDH1A1HSD17B10HSP90AA1PTPN1 | |
| SCHEMBL4731949 | 0.77 | HSPA5 (0.64) | HPGDALDH1A1HSD17B10HIF1ACYP2C9 | |
| SCHEMBL18857466 | 0.76 | HSP90AA1 (0.72) | HPGDALDH1A1HSD17B10HIF1AHSP90AA1 | |
| SCHEMBL11322770 | 0.75 | PTPN1 (0.51) | HPGDALDH1A1HSD17B10HIF1AHSP90AA1 | |
| SCHEMBL6670779 | 0.75 | PTPN1 (0.71) | HPGDALDH1A1HSD17B10PTPN1PTPN2 | |
| SCHEMBL9251915 | 0.75 | HPGD (0.75) | HPGDALDH1A1HSD17B10HIF1APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288265-B1 | HYDROXYBENZOIC ACID OR HYDROXYBENZAMIDE DERIVATIVES | NATIONAL SCIENCE COUNCIL (TW) | 2001-09-11 | — | — | US | disclosed |
| US-6121255-A | 7-(PHLOROGLUCIDAMIDO)CEPHALOSPORINS OR CEPHALOSPORIN 3'-PHLOROGLUCIDE ESTER ANTIBIOTICS | NATIONAL SCIENCE COUNCIL (TW) | 2000-09-19 | — | — | US | disclosed |